Search results for "Therapy Outcome"

Tumor hypoxia and therapeutic resistance

2008

For many years, the identification of tumor hypoxia, its systematic characterization and the assessment of its clinical relevance were not possible due to the lack of methods suitable for the routine measurement of intratumoral oxygen tensions in patients. In the late 1980s, a novel and clinically applicable standardized procedure was established enabling the determination of tumor oxygenation in accessible primary tumors, local recurrences, and metastatic lesions in patients using a computerized polarographic needle electrode system (Vaupel et al. 1991; Hockel et al. 1991). Within a relatively short period of time, the significance of tumor oxygenation for therapy outcome became evident in…

Influence of Personality Disorders on Therapy Outcome in Somatoform Disorders at 2-Year Follow-up

1999

Korkean vireystason hetket hyvän ja huonon hoitotuloksen pariterapiaprosesseissa

2017

Tutkimuksen tarkoituksena oli tutkia Relationaalinen mieli monitoimijaisten terapiadialogien muutoshetkissä -projektin pariterapioiden tuloksellisuutta sekä pariterapian tuloksellisuuteen vaikuttavia tekijöitä hyvän ja huonon hoitotuloksen pariterapiatapauksissa. Tuloksellisuustutkimuksen perusteella valitsimme yhden hyvän ja yhden huonon hoitotuloksen pariterapiatapaukset. Tutkimuksen aineistona olivat projektiin osallistuneiden pariterapia-asiakkaiden täyttämät Outcome Ratings Scale (ORS)- lomakkeet, Jyväskylän yliopiston tutkimus- ja opetusklinikalla videoidut neljä pariterapiaistuntoa ja terapiaistuntojen ajalta asiakkaiden ihon sähkönjohtavuuden mittaukset. Projektiin osallistuneiden p…

Cognitive behavior therapy for functional gastrointestinal disorders: is group treatment effective?

2003

Objective:The intention of this study was to evaluate therapy outcome of a cognitive-behavioral group treatment program for functional gastrointestinal disorders. As a particular characteristic, gastrointestinal symptoms were investigated independently from diagnostic categories on a dimensional basis, considering the persistence of symptoms as well as the aspect of severity.Methods:A total of 64 subjects participated in the 10-week treatment program, and 49 completed the study. Subjects underwent four assessments (baseline, pre-, post-treatment, 12-month follow-up), each comprising several self-rated questionnaires on gastrointestinal, somatoform, depressive, hypochondriacal and anxious sy…

Early and Later Predictors of Outcome in Brief Therapy: The Role of Real Relationship

2012

Objectives The study examined whether clients who continued longer in brief therapy reported stronger associations of real relationship and working alliance with therapy outcome than clients who received very brief treatment. It also examined whether real relationship and working alliance assessed early in treatment predicted outcome differently from that assessed later in therapy. Method Fifty clients (32 women; Mage = 22.3 years) were recruited from a university counseling center. Thirty-two clients (very brief therapy) completed the post-third session assessment of real relationship and working alliance, and 18 (brief therapy) had both the third and eighth assessment. Results The real re…

Sympathetic nervous system synchrony between participants of couple therapy

2017

Synchrony, or the moment-by-moment coordination between people in social situations, has been connected with increased liking and rapport. However, this type of synchrony is an underexplored area with regard to autonomic nervous system activity. The purpose of this research was to study physiological synchrony between participants in couple therapy by focusing on the sympathetic nervous system (SNS), which reflects arousal and emotional reactions. The data comprised 12 couple therapy cases (24 clients, 10 therapists) participating in the Relational Mind in Events of Change in Multiactor Therapeutic Dialogues (2013-2016) research project. Electrodermal activity (EDA) and heart rate were reco…

Spanish Adaptation and Validation of the Outcome Questionnaire OQ-30.2

2017

This study assessed the psychometric properties of a Spanish version of the Shortened Outcome Questionnaire (OQ-30.2, Lambert et al., 2004) validated with a sample of 546 patients in an outpatient mental health clinic and 100 non-clinical adults in Chile. Our results show that this measure has similar normative data to the original measure, with a cutoff score for the Chilean population set at 43.36, and the reliable change index at 14. This Spanish OQ-30.2 has good internal consistency (α = 0.90), has concurrent validity with the Depressive, Anxious, and Somatoform disorders measuring scale (Alvarado and Vera, 1991), and is sensitive to change during psychotherapy. Consistent with previous…

Benchmarking of cognitive-behavioral therapy for depression in efficacy and effectiveness studies--how do exclusion criteria affect treatment outcome?

2011

Abstract Objective: Little is known about how exclusion criteria applied in randomized controlled trials (RCTs) affect the transfer of psychotherapy outcome research to naturalistic settings. This study evaluated the effects of naturalistic depression therapies and benchmarked them with published RCTs. Method: Commonly used exclusion criteria were applied to n=338 depressive patients receiving cognitive-behavioral therapy. Outcomes of the resulting subsample eligible for RCTs were compared to those reported in RCTs. Results: Treatment outcomes of the total sample (d=1.16) and the subsample eligible for RCTs (d=1.15) were highly similar. Therapy outcome was worse than in high-quality RCTs (d…

Tumor Oxygenation and Its Relevance to Tumor Physiology and Treatment

2003

For many years, the identification of tumor hypoxia, its systematic characterization and the assessment of its clinical relevance were not possible due to lack of methods suitable for the routine measurement of intratumoral oxygen tensions in patients. In the late 1980s, a novel and clinically applicable standardized procedure was established enabling the determination of the tissue oxygenation status in primary tumors, local recurrences, and metastatic lesions in patients using a computerized polarographic needle electrode system. Within a relatively short period of time, the significance of tumor oxygenation for therapy outcome became evident in numerous experimental and clinical studies.

Suppressor effects in associations between patient attachment to therapist and psychotherapy outcome

2018

Abstract Objective Several studies propose that patient attachment to therapist is associated with therapy outcome. However, the magnitude of the effect is diverse, which might be explicable by suppressor effects and the new concept of pseudo‐security. Method Associations between patient attachment to therapist (client‐attachment‐to‐therapist‐scale [CATS]) and psychotherapy outcome (“global severity index” of the Symptom Check List) were evaluated in N = 368 patients. Multilevel models were performed. Results When tested in separate models, secure attachment to therapist was associated with a more favourable outcome (p < 0.05), whereas avoidant and preoccupied attachment to therapist were c…